Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the treatment method of several myeloma. Its synthesis or research is essential for ensuring the purity and basic safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Utilized in the remedy of prostate most cancers by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A vital compound while in the synthesis of imatinib, a drug that targets certain varieties of most cancers, like Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers such as breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their examine is very important for optimizing the production course of action and guaranteeing high purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilised to treat breast most cancers, and these intermediates are linked to its production.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the remedy of breast most cancers. Several intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug effective in dealing with cancers such as ovarian, breast, and lung cancer.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the remedy of colorectal most cancers and modest mobile lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is linked to the synthesis of adamantane derivatives, that have various programs, which include antiviral Attributes.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for type 2 diabetes that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with CAS NO. 155405-80-4 the synthesis of assorted gluconic acid derivatives, which are used in meals, pharmaceutical, and industrial programs.
Canagliflozin Intermediate two: A precursor in the synthesis of canagliflozin, a medication utilised to control form two diabetic issues by inhibiting sodium-glucose co-transporter two Canagliflozin Intermediate2 (SGLT2).